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Janumet is an oral prescription medication that combines two active blood-sugar-lowering ingredients: sitagliptin, a DPP-4 inhibitor, and metformin, a biguanide. It is prescribed alongside diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Sitagliptin works by increasing insulin release and decreasing glucagon levels, while metformin reduces glucose production in the liver and improves insulin sensitivity. This dual-action formula helps manage daily blood sugar levels effectively and prevents long-term complications associated with diabetes.